The DNA methylation landscape of advanced prostate cancer | 私立大學五星教授網

由 R Lakshminarasimhan 著作 · 2016 · 被引用 112 次 — DNA methylation is a complex epigenetic mechanism crucial to regulating gene expression in normal and tumor cells. Methylation of CpGs at the promoters of genes ...

由 A Nishiyama 著作 · 2021 · 被引用 363 次 — Disruption of DNA methylation control mechanisms causes a variety of diseases, including cancer. Cancer cells are characterized by aberrant DNA ...

由 M Kulis 著作 · 2010 · 被引用 1725 次 — It is commonly known that inactivation of certain tumor-suppressor genes occurs as a consequence of hypermethylation within the promoter regions and a numerous ...

由 WJ Locke 著作 · 2019 · 被引用 351 次 — MSP is used to amplify cancer DNA from hypermethylated promoters. With ctDNA assays, the cancer-originating DNA is rare compared to background off-target DNA, ...

DNA methylation in cancer plays a variety of roles, helping to change the healthy cells by regulation of gene expression to a cancer cells or a diseased ...

由 SG Zhao 著作 · 2020 · 被引用 224 次 — Several studies have compared DNA methylation patterns between primary prostate cancer (PCa) and benign prostate tissue, and between subtypes of ...

由 Z Zhu 著作 · 2024 — MethMarkerDB collects and analyzes WGBS data from various cancer types to identify cancer DNA methylation biomarkers across the whole genome.

由 S Bhootra 著作 · 2023 · 被引用 10 次 — While aberrant methylation is associated with cancer, DNA demethylation is also linked with early carcinogenesis. Changes in the demethylation ...