DNA methylation and its basic function | 私立大學五星教授網

DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factor(s) to DNA. During development, the pattern of DNA methylation in the genome changes as a result of a dynamic

由 LD Moore 著作 · 2013 · 被引用 4413 次 — DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription ...

When located in a gene promoter, DNA methylation typically acts to repress gene transcription. In mammals, DNA methylation is essential for normal development ...

Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression.

2012年7月11日 — DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription ...

DNA methylation is a well-characterized epigenetic modification that plays a key role in gene regulation, with alterations contributing to tumorigenesis in PCa.

由 S Kumar 著作 · 2021 · 被引用 127 次 — Plants use methylation of viral genomic DNA to restrict its replication, while virus encodes viral suppressor proteins to protect it from getting methylated ( ...

2023年11月28日 — DNA methylation plays a critical role in regulating gene expression by turning genes “on” or “off.” When certain regions of DNA are methylated, ...

由 A Razin 著作 · 1980 · 被引用 2683 次 — DNA methylation is a key element in the hierarchy of control mechanisms that govern vertebrate gene function and differentiation.

由 BM Tibben 著作 · 2023 · 被引用 8 次 — DNA methylation is a well-studied epigenetic modification that has key roles in regulating gene expression, maintaining genome integrity, and determining ...