What is microsatellite instability? | 私立大學五星教授網

Listen to pronunciation. (MY-kroh-SA-teh-lite in-stuh-BIH-lih-tee) A change that occurs in certain cells (such as cancer cells) in which the number of repeated DNA bases in a microsatellite (a short, repeated sequence of DNA) is different from what it was

2017年10月11日 — 3. Zoran Gatalica.,et al. High microsatellite instability (MSI-H) colorectal carcinoma: a brief review of predictive biomarkers in the era of ...

2019年6月18日 — 微星體不穩定性(microsatellite instability，MSI)是大腸癌發生的重要分子機制之一，約佔sporadic大腸直腸癌之15%，對大腸直腸癌具有重要臨床意義。MSI ...

Microsatellite instability (MSI) is the condition of genetic hypermutability (predisposition to mutation) that results from impaired DNA mismatch repair ...

由 K Li 著作 · 2020 · 被引用 432 次 — The instability of one site is called low microsatellite instability (MSI-L), and the instability of two or more sites is called high ...

2023年3月6日 — Specific genes monitor the DNA for mistakes and then repair them. This built-in ability to error-correct is called mismatch repair, and the ...

由 CR Boland 著作 · 2010 · 被引用 2681 次 — Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatch repair activity. MSI is detected in about 15% of all ...

Microsatellite instability (MSI) is defined as somatic alterations in microsatellite sequences due to the deletion or insertion of one or more repeat units, ...

由 R Bonneville 著作 · 2017 · 被引用 1294 次 — Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic microsatellites and is caused by defects in the ...