They inhibit viral maturation by binding to protease. HIV protease cleaves the HIV GAG-POL precursor polyprotein and ensures that the new virions are mature and ...
Protease inhibitors (PIs) block protease (an HIV enzyme). By blocking protease, PIs prevent new (immature) HIV from becoming a mature virus that can infect other CD4 cells.
2017年9月1日 — The human immunodeficiency virus (HIV) protease inhibitors are a broad class of agents that are widely used in the therapy and prevention of ...
Protease inhibitors treat certain viral infections by preventing the virus from making more copies of itself. They're a critical part of HIV treatment.
2023年5月22日 — Protease inhibitors don't cure HIV. But by blocking proteases, they can stop HIV from reproducing itself. As such, they lower the body's viral ...
Protease inhibitors work to reduce the amount of HIV virus in the blood, also known as viral load. This slows the progression of HIV and helps treat symptoms.
由 Z Lv 著作 · 2015 · 被引用 626 次 — 1 HIV protease inhibitor is one of the most important components in the combination therapy. In the preferred antiretroviral combination ...
Protease inhibitors are medications that help slow the progression of HIV by blocking the enzyme “protease,” which HIV cells need to develop and mature.
These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic cleavage of protein ...
HIV protease inhibitors (PIs) inhibit HIV-1 and HIV-2 proteases and prevent cleavage of the gag-pol polyprotein during maturation of the newly formed viral ...
They inhibit viral maturation by binding to protease. HIV protease cleaves the HIV GAG-POL precursor polyprotein and ensures that the new virions are mature and ...
