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The L-type channel is the primary route for Ca2+ entry into cardiac, skeletal, and smooth muscles. The skeletal muscle L-type channel acts as a voltage sensor for excitation-contraction (E-C) coupling in skeletal muscle, presumably linking membrane depola

L-type calcium channels are responsible for the excitation-contraction coupling of skeletal, smooth, cardiac muscle, and for aldosterone secretion in endocrine ...

L-Type Calcium Channels are high-voltage-activated channels found in various cells, including excitable and non-excitable cells. They play a crucial role in ...

由 J Striessnig 著作 · 2014 · 被引用 262 次 — L-type calcium channels (Cav1) represent one of the three major classes (Cav1–3) of voltage-gated calcium channels. They were identified as the target of ...

由 P Mesirca 著作 · 2024 · 被引用 4 次 — L-type Ca2+ channels are required for multiple functions in the heart, including regulation of early organogenesis, structural development, ...

由 DJ Triggle 著作 · 1998 · 被引用 73 次 — The L-type calcium channel is responsible for normal myocardial contractility and for vascular smooth muscle contractility. In contrast, T-type calcium channels ...

由 D Lipscombe 著作 · 2002 · 被引用 95 次 — Voltage-gated calcium channels are essential for coupling membrane depolarization to the influx of calcium in all excitable cells.

由 D Lipscombe 著作 · 2004 · 被引用 540 次 — L-type calcium channels couple membrane depolarization in neurons to numerous processes including gene expression, synaptic efficacy, and cell survival.